Cotinine [486-56-6]
HY-B1178
CAS Number486-56-6
Product group Chemicals
Estimated Purity99.56
Molecular Weight176.219
Overview
- SupplierMedChem Express
- Product NameCotinine [486-56-6]
- Delivery Days Customer5
- CAS Number486-56-6
- CertificationResearch Use Only
- Estimated Purity99.56
- Molecular FormulaC10H12N2O
- Molecular Weight176.219
- Scientific DescriptionCotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors (nAChR) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases[1][2][3][4][5].
- SMILESO=C1N(C)[C@H](C2=CC=CN=C2)CC1
- Storage Instruction2°C to 8°C
- UNSPSC12352200
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