COX-2-IN-14 [2428387-48-6]
HY-147692
CAS Number2428387-48-6
Product group Chemicals
Molecular Weight386.36
Overview
- SupplierMedChem Express
- Product NameCOX-2-IN-14 [2428387-48-6]
- Delivery Days Customer10
- CAS Number2428387-48-6
- CertificationResearch Use Only
- Molecular FormulaC18H18N4O6
- Molecular Weight386.36
- Scientific DescriptionCOX-2-IN-14 (compound 2a) is a potent and selective COX-2 (cyclooxygenase-2) inhibitor. COX-2-IN-14 shows effective binding at the active site of COX-2 co-crystal. COX-2-IN-14 exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity in mice[1].
- SMILESCCOC(C1=C(C=C(C([O-])=N1)C#N)C(C2=CC=C(C=C2)[N+]([O-])=O)=O)=O.C[NH2+]C
- UNSPSC12131703