COX-2-IN-17 [2411390-10-6]

MedChem Express

COX-2-IN-17 [2411390-10-6]

10

2411390-10-6

Research Use Only

C20H23ClN6O2

414.89

COX-2-IN-17 (compound 10) is a potent and BBB-penetrated COX-2 (cyclooxygenase-2) inhibitor, with an IC50 of 0.02 microM. COX-2-IN-17 shows anti-inflammatory and analgesic activities. COX-2-IN-17 attenuates hyperalgesia in the neurogenic phase as well as the inflammatory phase[1].

N[C@@H](CC1=CN(C2=NC(Cl)=NC(N3CCCCC3)=N2)C4=CC=CC=C14)C(OC)=O

12131703