COX-2-IN-26 [2413565-19-0]

MedChem Express

COX-2-IN-26 [2413565-19-0]

10

2413565-19-0

Research Use Only

C23H21N7OS3

507.65

COX-2-IN-26 is a potent, selective and orally active COX-2 inhibitor with IC50 values of 10.61, 0.067, 1.96 microM for COX-1, COX-2, 15-LOX, respectively. COX-2-IN-26 shows anti-inflammatory activity. COX-2-IN-26 shows gastrointestinal safety profile[1].

O=C1N(C2=CC=CC=C2)/C(SC1)=N\N=C(CNC3=NC(N4C(SC)=NC5=C4C=CC=C5)=CS3)/C

12131703