COX-2-IN-30 [1160498-08-7]
HY-149269
CAS Number1160498-08-7
Product group Chemicals
Molecular Weight384.41
Overview
- SupplierMedChem Express
- Product NameCOX-2-IN-30 [1160498-08-7]
- Delivery Days Customer10
- CAS Number1160498-08-7
- CertificationResearch Use Only
- Molecular FormulaC17H16N6O3S
- Molecular Weight384.41
- Scientific DescriptionCOX-2-IN-30 is a benzenesulfonamide derivative, as well as an orally active and dual inhibitor of COX (IC50=49 nM for COX-2, 10.4 microM for COX-1) and 5-LOX (IC50=2.4 microM). COX-2-IN-30 also inhibits transmembrane hCA IX and hCA XII isoform with nanomolar calss Ki values. COX-2-IN-30 exhibits analgesic, anti-inflammatory, and ulcerogenic activities, and does not show acute gastric effect[1].
- SMILESO=C(C1=C(N(N=C1)C2=CC=C(C=C2)S(N)(=O)=O)N)N/N=C/C3=CC=CC=C3
- UNSPSC12131703