Bio-Connect

COX-2-IN-31

HY-149270
MedChem Express
Molecular Weight400.41
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    COX-2-IN-31
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C17H16N6O4S
  • Molecular Weight
    400.41
  • Scientific Description
    COX-2-IN-31 (compound 7b) is an orally active and dual inhibitor of COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 microM). COX-2-IN-31 also inhibits transmembrane hCA IX(Ki=48.9 nM) and hCA XII(Ki=5.8 nM) activity. COX-2-IN-31 exhibits anti-inflammatory and analgesic activity[1].
  • SMILES
    NC1=C(C=NN1C2=CC=C(C=C2)S(N)(=O)=O)C(N/N=C/C3=CC=C(C=C3)O)=O
  • UNSPSC
    12131703