COX-2-IN-9

MedChem Express

COX-2-IN-9

10

Research Use Only

C25H23N5O4S2

521.61

COX-2-IN-9 (compound 7a) is a potent, selective, and orally active inhibitor of COX-2 with an IC50 of 10.17 uM. COX-2-IN-9 has higher COX-2 selectivity than Celecoxib. COX-2-IN-9 shows good in vivo anti-inflammatory and low ulcerogenic activity[1].

C/C(C1=CC=C(C=C1)NC(CSC2=NN(C(C3=CC=CC=C3)=N2)C4=CC=C(C=C4)S(C)(=O)=O)=O)=N\O

12352200