COX-2/15-LOX-IN-4

MedChem Express

COX-2/15-LOX-IN-4

14

Research Use Only

C23H20FN3OS

405.49

COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor of COX-2/15-LOX with IC50s of 0.075 microM and 1.97 microM, respectively. COX-2/15-LOX-IN-4 can inhibit LPS-induced cell production of promoting cytokines (IL-6, ROS) with specific anti-inflammatory activity[1].

COC(C=C1)=CC=C1C2=NC3=C(C(CCCC4)=C4S3)C(NC5=CC=C(F)C=C5)=N2

12352200