COX-2/15-LOX-IN-5 [443790-30-5]

TargetMol Chemicals

COX-2/15-LOX-IN-5 [443790-30-5]

16

Research Use Only

C25H21N3O3S

443.52

COX-2/15-LOX-IN-5 (Compound 4f) functions as a dual inhibitor of COX-2 and 15-LOX, demonstrating both anti-inflammatory and antioxidant properties [1]. This compound effectively reduces NF-kappaB activation in RAW 264.7 macrophages that is induced by lipopolysaccharide.

S(CC(NC1=CC=C(OC)C=C1)=O)C=2N(C(=O)C(=CC3=CC=CC=C3)N2)C4=CC=CC=C4

-20°C

51202000