COX-2/15-LOX/mPGES1-IN-1

MedChem Express

COX-2/15-LOX/mPGES1-IN-1

14

Research Use Only

C19H16N2O5

352.34

COX-2/15-LOX/mPGES1-IN-1 (Compound 2c) is an inhibitor of COX-2, 15-LOX, and mPGES-1 enzymes with IC50 values of 0.057, 2.39, and 2.8 microM, respectively. COX-2/15-LOX/mPGES1-IN-1 possesses anti-inflammatory activity and can inhibit rat paw edema in vivo experiments[1].

O=C(N/N=C/C1=COC2=C(C=CC(OC)=C2)C1=O)OCC3=CC=CC=C3

12352200