COX-2/5-LOX-IN-1 [2410384-50-6]

TargetMol Chemicals

COX-2/5-LOX-IN-1 [2410384-50-6]

72

Chemical

Research Use Only

COX-2/5-LOX-IN-1

C14H10ClN3O4S2

383.83

COX-2/5-LOX-IN-1 (compound 3a), a benzothiophen-2-yl pyrazole carboxylic acid derivative, is a potent dual inhibitor of COX-2 and 5-LOX, exhibiting superior analgesic and anti-inflammatory properties compared to Celecoxib and Indomethacin. It demonstrates strong inhibitory activity against COX-1, COX-2, and 5-LOX, with IC50 values of 12.13 microM, 0.4 microM, and 4.96 microM, respectively [1].

3 years

C(O)(=O)C=1C=C(N(N1)C2=CC=C(S(N)(=O)=O)C=C2)C=3SC(Cl)=CC3

-20°C

51202000