COX-2/5-LOX-IN-2 [2410384-59-5]

TargetMol Chemicals

COX-2/5-LOX-IN-2 [2410384-59-5]

72

Chemical

Research Use Only

COX-2/5-LOX-IN-2

C18H13N3O4S2

399.44

COX-2/5-LOX-IN-2 is a benzothiophen-2-ylpyrazole carboxylic acid derivative that inhibits both COX-2 and 5-LOX. COX-2/5-LOX-IN-2 (5b) has IC50 values of 5.40, 0.01, and 1.78 microM for COX-1, COX-2, and 5-LOX, respectively, and exhibits greater analgesic and anti-inflammatory activities than Celecoxib and Indomethacin.

3 years

C(O)(=O)C=1C=C(N(N1)C2=CC=C(S(N)(=O)=O)C=C2)C3=CC=4C(S3)=CC=CC4

-20°C

51202000