COX-2/5-LOX-IN-3 [2481484-51-7]

MedChem Express

COX-2/5-LOX-IN-3 [2481484-51-7]

10

2481484-51-7

Research Use Only

C17H16ClN3O2S

361.85

COX-2/5-LOX-IN-3 (compound 5b) is a potent and dual COX-2/5-LOX inhibitor with IC50 values of 45.73, 5.45 and 4.33 microM for COX-1, COX-2, and 5-LOX, respectively. COX-2/5-LOX-IN-3 has the potential for the research of inflammation diseases[1].

O=C(NC1=C(C#N)C(C2=CC=C(Cl)C=C2)=CS1)CN3CCOCC3

12131703