COX17 Polyclonal Antibody
RD253364A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCOX17
Overview
- SupplierReddot Biotech
- Product NameCOX17 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.1 mg/ml
- ConjugateUnconjugated
- Gene ID10063
- Target nameCOX17
- Target descriptioncytochrome c oxidase copper chaperone COX17
- Target synonymsCOX17 cytochrome c oxidase assembly homolog; COX17, cytochrome c oxidase copper chaperone; cytochrome c oxidase 17 copper chaperone; cytochrome c oxidase assembly homolog 17; cytochrome c oxidase copper chaperone; human homolog of yeast mitochondrial copper recruitment
- HostRabbit
- IsotypeIgG
- Scientific DescriptionCytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203