Coxsackievirus A16 VP4 (68a.a, sf9, Fc)

MedChem Express

Coxsackievirus A16 VP4 (68a.a, sf9, Fc)

10

Research Use Only

Coxsackievirus A16 (CVA16) can cause hand-foot-and-mouth disease (HFMD). CVA16 is a small, non-enveloped, icosahedral particle containing a single-stranded, positive-sense viral RNA genome of approximately 7.4 kb in length. CVA16 can be cleaved by viral proteases into 4 structural (VP1 to VP4) and 7 nonstructural (2A to 2C, and 3A to 3D) proteins. CVA16 interacts with its host receptors (cell surface heparan sulfate glycosaminoglycans and SCARB2 as its uncoating receptor) to enter into susceptible cells. Upon binding, CVA16 mature virions may transform to an uncoating intermediate state. Coxsackievirus A16 VP1 Protein is one of the capsid subunit protein of cleaved CVA16[1][2]. Coxsackievirus A16 VP4 Protein (68a.a, sf9, Fc) is the recombinant Virus-derived Coxsackievirus A16 VP4 protein, expressed by Sf9 insect cells , with C-rFc labeled tag.

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