CP-465022 (maleate) [199656-46-7]

MedChem Express

CP-465022 (maleate) [199656-46-7]

10

199656-46-7

Research Use Only

h302,p264-p270-p330-p501

C30H28ClFN4O5

579.02

CP-465022 Maleate is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes[1][2].

O=C1N(C2=CC=CC=C2Cl)C(/C=C/C3=NC(CN(CC)CC)=CC=C3)=NC4=C1C=C(F)C=C4.O=C(O)/C=C\C(O)=O

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