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ProductsBack/CP-724714 [383432-38-0]

CP-724714 [383432-38-0]

Research Use Only
HY-14674
MedChem Express
CAS Number383432-38-0
DownloadMSDS
Product group Chemicals
Estimated Purity98.53
Molecular Weight469.55
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CP-724714 [383432-38-0]
  • Delivery Days Customer
    9
  • CAS Number
    383432-38-0
  • Certification
    Research Use Only
  • Estimated Purity
    98.53
  • Molecular Formula
    C27H27N5O3
  • Molecular Weight
    469.55
  • Scientific Description
    CP-724714 is a potent, selective and orally active ErbB2 (HER2) tyrosine kinase inhibitor, with an IC50 of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC50=6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities[1][2].
  • SMILES
    O=C(COC)NC/C=C/C1=CC2=C(N=CN=C2C=C1)NC3=CC=C(C(C)=C3)OC4=CC=C(N=C4)C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200