CP-99994 (hydrochloride) [145148-39-6]
HY-12145
CAS Number145148-39-6
Product group Chemicals
Molecular Weight369.33
Overview
- SupplierMedChem Express
- Product NameCP-99994 (hydrochloride) [145148-39-6]
- Delivery Days Customer9
- CAS Number145148-39-6
- CertificationResearch Use Only
- Molecular FormulaC19H26Cl2N2O
- Molecular Weight369.33
- Scientific DescriptionCP-99994 hydrochloride is a Tachykinin neurokinin 1 (NK-1) receptor antagonist with a Ki of 0.25 nM. CP-99994 hydrochloride prevents colorectal sensitization in the context of visceral hypersensitivity. CP-99994 hydrochloride reduces colorectal hypersensitivity induced by acetic acid injections in a model of bladder-colon cross-sensitization. CP-99994 hydrochloride attenuates the neuroglial interactions and MAPK-p38 phosphorylation associated with visceral hypersensitivity[1].
- SMILESCOC(C=CC=C1)=C1CN[C@@H]2[C@H](C3=CC=CC=C3)NCCC2.Cl.Cl
- UNSPSC12352200
![CP 99994 dihydrochloride [145148-39-6]](https://www.targetmol.com/group3/M00/02/7A/CgoaEWY7LwWEexzbAAAAAG81-Do215.png)