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CPI-455

HY-100421
MedChem Express
CAS Number1628208-23-0
DownloadMSDS
Product group Chemicals
Estimated Purity98.95
Molecular Weight278.31
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CPI-455 [1628208-23-0]
  • Delivery Days Customer
    10
  • CAS Number
    1628208-23-0
  • Certification
    Research Use Only
  • Estimated Purity
    98.95
  • Molecular Formula
    C16H14N4O
  • Molecular Weight
    278.31
  • Scientific Description
    CPI-455 is a specific, pan- KDM5 inhibitor with an IC 50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents [1] .
  • SMILES
    N#CC1=C2NC(C3=CC=CC=C3)=C(C(C)C)C(N2N=C1)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200