CREB-binding Protein (mouse) (rec.) (His) (highly active)

AdipoGen Life Sciences

CREB-binding Protein (mouse) (rec.) (His) (highly active)

10

Research Use Only

>95%

CREB-binding protein

CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300. - Protein. Mouse full-length CREB-binding protein fused at the C-terminus to a His-tag. Source: Sf21 cells. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50-100mM imidazole and 10% glycerol. Purity: >95% (SDS-PAGE). CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.

-20°C,-80°C

12352202