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Crebanine [25127-29-1]

M19274
AbMole BioScience
CAS Number25127-29-1
Product group Chemicals
Estimated Puritymore then99.0%
Molecular Weight339.39
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Crebanine [25127-29-1]
  • Delivery Days Customer
    7
  • CAS Number
    25127-29-1
  • Certification
    Research Use Only
  • Estimated Purity
    more then99.0%
  • Molecular Formula
    C20H21NO4
  • Molecular Weight
    339.39
  • Scientific Description
    Crebanine, an alkaloid from Stephania venosa, induces G1 arrest and apoptosis in human cancer cells. Crebanine exhibits anti-inflammatory activity via suppressing MAPKs and Akt signaling. Crebanine also possesses antiarrhythmic effect. Furthermore, Crebanine can inhibit the PI3K/Akt/mTOR pathway and generate reactive oxygen species, thereby blocking tumour proliferation and migration. In animal studies, Crebanine has also demonstrated central and peripheral analgesic and anti-inflammatory activity.
  • SMILES
    COC1=C(OC)C2=C(C=C1)C3=C4C(C2)N(C)CCC4=CC5=C3OCO5
  • Storage Instruction
    4°C, protect from light
  • UNSPSC
    12161508

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