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ProductsBack/Crenolanib [670220-88-9]
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Crenolanib [670220-88-9]

Research Use Only
T2677
TargetMol Chemicals
CAS Number670220-88-9
DownloadMSDS
Product group Chemicals
Molecular Weight443.54
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Crenolanib [670220-88-9]
  • Delivery Days Customer
    9
  • CAS Number
    670220-88-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Crenolanib
  • Molecular Formula
    C26H29N5O2
  • Molecular Weight
    443.54
  • Scientific Description
    Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRalpha/beta and FLT3 (IC50s: 11, 3.2, and 4 nM).
  • Shelf life instruction
    3 years
  • SMILES
    CC1(COc2ccc3n(cnc3c2)-c2ccc3cccc(N4CCC(N)CC4)c3n2)COC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Heinrich MC, et al.Crenolanib inhibits the drug-resistant PDGFRA D842V mutation associated with imatinib-resistant gastrointestinal stromal tumors. Clin Cancer Res, 2012, Jun 27.
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