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ProductsBack/CrkL antibody

CrkL antibody

GTX10907
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetCRKL
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Overview

  • Supplier
    GeneTex
  • Product Name
    CrkL antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1/200-1/500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1399
  • Target name
    CRKL
  • Target description
    CRK like proto-oncogene, adaptor protein
  • Target synonyms
    crk-like protein; v-crk avian sarcoma virus CT10 oncogene homolog-like
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDP46109
  • Protein Name
    Crk-like protein
  • Scientific Description
    This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L. Hallock PT et al., 2010 Nov 1, Genes Dev
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