CrkL antibody
GTX10907
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetCRKL
Overview
- SupplierGeneTex
- Product NameCrkL antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1/200-1/500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID1399
- Target nameCRKL
- Target descriptionCRK like proto-oncogene, adaptor protein
- Target synonymscrk-like protein, v-crk avian sarcoma virus CT10 oncogene homolog-like
- HostGoat
- IsotypeIgG
- Protein IDP46109
- Protein NameCrk-like protein
- Scientific DescriptionThis gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Hallock PT, Xu CF, Park TJ, et al. Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L. Genes Dev. 2010,24(21):2451-61. doi: 10.1101/gad.1977710Read this paper





![Untreated (–) and treated (+) K562 whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with CrkL (phospho Tyr207) antibody [HL3176] (GTX640694) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX640694/GTX640694_T-45488_20240802_WB_treatment_CIP_24080602_486.webp)
