CrkL antibody
GTX10907
Overview
- SupplierGeneTex
- Product NameCrkL antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1/200-1/500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID1399
- Target nameCRKL
- Target descriptionCRK like proto-oncogene, adaptor protein
- Target synonymscrk-like protein; v-crk avian sarcoma virus CT10 oncogene homolog-like
- HostGoat
- IsotypeIgG
- Protein IDP46109
- Protein NameCrk-like protein
- Scientific DescriptionThis gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L. Hallock PT et al., 2010 Nov 1, Genes DevRead more