CRMP1 Polyclonal Antibody

Reddot Biotech

CRMP1 Polyclonal Antibody

5

0.4 mg/ml

CRMP1

collapsin response mediator protein 1

CRMP-1; dihydropyrimidinase-like 1; dihydropyrimidinase-related protein 1; DPYSL1; DRP1; DRP-1; inactive dihydropyrimidinase; ULIP-3; unc-33-like phosphoprotein 3

Collapsin response mediator protein 1, encoded by theCRMP1gene, is a humanproteinof theCRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.

-20°C

12352203