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CRTAC1 antibody

GTX119558
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCRTAC1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CRTAC1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID55118
  • Target name
    CRTAC1
  • Target description
    cartilage acidic protein 1
  • Target synonyms
    acidic secreted protein in cartilage; ASPIC; ASPIC1; cartilage acidic protein 1; CEP68; CEP-68; chondrocyte expressed protein 68 kDa CEP-68; LOTUS
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NQ79
  • Protein Name
    Cartilage acidic protein 1
  • Scientific Description
    This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CRTAC1 enhances the chemosensitivity of non-small cell lung cancer to cisplatin by eliciting RyR-mediated calcium release and inhibiting Akt1 expression.
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  • Sex-Specific Protection of Osteoarthritis by Deleting Cartilage Acid Protein 1. Ge X et al., 2016, PLoS One
    Read more