CRTAM Polyclonal Antibody

Elabscience

CRTAM Polyclonal Antibody

12

Western Blot, ImmunoHistoChemistry

ELISA IHC

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

CRTAM

cytotoxic and regulatory T cell molecule

CD355, cytotoxic and regulatory T-cell molecule, class-I MHC-restricted T-cell-associated molecule

Rabbit

IgG

Cytotoxic and regulatory T-cell molecule

The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

-20°C

41116161