CRTh2 antagonist 4 [916046-55-4]

MedChem Express

CRTh2 antagonist 4 [916046-55-4]

5

916046-55-4

Research Use Only

C20H14ClFN2O5

416.79

CRTh2 antagonist 4 (compound 58) is an inhibitor (IC50: 212 nM) of TH2 lymphocyte (CRTH2 or DP2) receptor with high binding affinity (Ki= 37 nM). CRTh2 antagonist 4 can be used in the study of severe allergic diseases[1].

O=C(O)CN1C(C2(C(N(CC3=CC=CC=C3F)C(C2)=O)=O)C4=C1C=CC(Cl)=C4)=O

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