CSK-IN-1

MedChem Express

CSK-IN-1 [2380027-49-4]

10

2380027-49-4

Research Use Only

98.61

C34H32ClFN8O4

671.12

CSK-IN-1 (compound 13) is a potent, orally active c-terminal Src kinase (CSK) with IC 50 values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. CSK-IN-1 shows the ability to increase T cell proliferation induced by T cell receptor signaling [1] .

O=C(C1=NN(C2CCN(C(CC(C)(C#N)C)=O)CC2)C3=C1C=C(F)C=C3)NC4=CC=C(NC(C5=C6C=CC(OC)=CN6N=C5)=O)C(Cl)=C4

-20°C,2°C to 8°C

12352200