
Western blot All lanes: CSNK1G2 antibody at 4.21ug/ml Lane 1: Mouse gonadal tissue Lane 2: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 47 kDa Observed band size: 47 kDa
CSNK1G2 Antibody
CSB-PA006070ESR2HU
ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCSNK1G2
Overview
- SupplierCusabio
- Product NameCSNK1G2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1455
- Target nameCSNK1G2
- Target descriptioncasein kinase 1 gamma 2
- Target synonymscasein kinase I; casein kinase I isoform gamma-2; CK1g2; CKI-gamma 2
- HostRabbit
- IsotypeIgG
- Protein IDP78368
- Protein NameCasein kinase I isoform gamma-2
- Scientific DescriptionSerine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161








