CSRM617 (Standard)
HY-122611R
Product group Assays
Overview
- SupplierMedChem Express
- Product NameCSRM617 (Standard) [787504-88-5]
- Delivery Days Customer5
- CertificationResearch Use Only
- Scientific DescriptionCSRM617 (Standard) is the analytical standard of CSRM617. This product is intended for research and analytical applications. CSRM617 is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor) with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. CSRM617 induces apoptosis by appearance of cleaved Caspase-3 and PARP. CSRM617 is well tolerated in the prostate cancer mouse model [1]
- UNSPSC41116135