CT-721

MedChem Express

CT-721 [1388710-60-8]

10

1388710-60-8

Research Use Only

C30H29ClN6O

525.04

CT-721 is a potent and time-dependent Bcr-Abl kinase inhibitor with an IC 50 of 21.3 nM for wild-type Bcr-Abl kinase, and possesses anti-chronic myeloid leukemia (CML) activities [1] . CT-721 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CC1=CC=C(NC(C2=CC=C([C@@H](N3CCN(C)CC3)CC4)C4=C2)=O)C=C1C#CC5=CN=C6N5N=C(Cl)C=C6

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