Overview
- SupplierGeneTex
- Product NameCTDSP2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.96 mg/ml
- IsotypeIgG
- Scientific DescriptionPreferentially catalyzes the dephosphorylation of Ser-5 within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203