CTDSP2 antibody

GeneTex

CTDSP2 antibody

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

CTDSP2

CTD small phosphatase 2

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; conserved gene amplified in osteosarcoma; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2; NLI-interacting factor 2; nuclear LIM interactor-interacting factor 2; OS4; protein OS-4; PSR2; SCP2; small CTD phosphatase 2; small C-terminal domain phosphatase 2

Rabbit

IgG

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

Preferentially catalyzes the dephosphorylation of Ser-5 within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203