CTL-12
HY-149541
Overview
- SupplierMedChem Express
- Product NameCTL-12
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC22H21ClN4O4
- Molecular Weight440.88
- Scientific DescriptionCTL-12 is an inhibitor of fatty acid synthase (FASN) (IC50: 2.5 microM) and can induce apoptosis. CTL-12 blocks the cell cycle in the Sub-G1/S phase, upregulates the expression of caspase-9 and the apoptosis marker Bax, and downregulates the anti-apoptotic marker Bcl-xL. CTL-12 inhibits de novo lipogenesis, blocks the metabolic demands of tumor cells, and is commonly used in breast and colorectal cancer research[1].
- SMILESO=C(C1=CC=C2C(N=C(C3=C(O)C=CC(Cl)=C3)N2)=C1)N4CCN(C(C5(O)CC5)=O)CC4
- UNSPSC12131703