Bio-Connect

CTL-12

HY-149541
MedChem Express
Molecular Weight440.88
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CTL-12
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C22H21ClN4O4
  • Molecular Weight
    440.88
  • Scientific Description
    CTL-12 is an inhibitor of fatty acid synthase (FASN) (IC50: 2.5 microM) and can induce apoptosis. CTL-12 blocks the cell cycle in the Sub-G1/S phase, upregulates the expression of caspase-9 and the apoptosis marker Bax, and downregulates the anti-apoptotic marker Bcl-xL. CTL-12 inhibits de novo lipogenesis, blocks the metabolic demands of tumor cells, and is commonly used in breast and colorectal cancer research[1].
  • SMILES
    O=C(C1=CC=C2C(N=C(C3=C(O)C=CC(Cl)=C3)N2)=C1)N4CCN(C(C5(O)CC5)=O)CC4
  • UNSPSC
    12131703