CTP 518(Atazanavir, deuterated)

Biorbyt

CTP 518(Atazanavir, deuterated) [1092540-56-1]

16

1092540-56-1

Research Use Only

C38H37D15N6O7.H2O4S

818.03

A partially dueterated analog of Atazanavir, an oral HIV protease inhibitor; A deuterium-containing medicine with improved ADME properties; Compound 120 showed an approximately 50% increase in half life compared with Atazanavir.

[2H]C([2H])([2H])OC(=O)N[C@@H](C(C)(C)C)C(=O)NN(CC1=CC=C(C=C1)C2N=CC=CC=2)C[C@H](O)[C@H](CC3=CC=CC=C3)NC(=O)[C@@H](NC(=O)OC([2H])([2H])[2H])C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

12352200