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CTP synthase antibody [N1C1]

GTX105265
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCTPS1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CTP synthase antibody [N1C1]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1503
  • Target name
    CTPS1
  • Target description
    CTP synthase 1
  • Target synonyms
    CTPS, GATD5, GATD5A, IMD24, CTP synthase 1, CTP synthetase 1, UTP--ammonia ligase 1, cytidine 5'-triphosphate synthetase, cytidine 5-prime triphosphate synthetase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP17812
  • Protein Name
    CTP synthase 1
  • Scientific Description
    The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chang CC, Jeng YM, Peng M, et al. CTP synthase forms the cytoophidium in human hepatocellular carcinoma. Exp Cell Res. 2017,361(2):292-299. doi: 10.1016/j.yexcr.2017.10.030
    Read this paper
  • Calise SJ, Purich DL, Nguyen T, et al. 'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway. J Cell Sci. 2016,129(15):3042-52. doi: 10.1242/jcs.183400
    Read this paper
  • Chang CC, Lin WC, Pai LM, et al. Cytoophidium assembly reflects upregulation of IMPDH activity. J Cell Sci. 2015,128(19):3550-5. doi: 10.1242/jcs.175265
    Read this paper
  • Aughey GN, Grice SJ, Shen QJ, et al. Nucleotide synthesis is regulated by cytoophidium formation during neurodevelopment and adaptive metabolism. Biol Open. 2014,3(11):1045-56. doi: 10.1242/bio.201410165
    Read this paper