Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CTP synthase antibody [N1C1] (GTX105265) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
![Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CTP synthase antibody [N1C1] (GTX105265) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](https://www.genetex.com/upload/website/prouct_img/normal/GTX105265/GTX105265_39939_20180420_WB_2_w_23060120_218.webp "Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CTP synthase antibody [N1C1] (GTX105265) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.")
Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CTP synthase antibody [N1C1] (GTX105265) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
CTP synthase antibody [N1C1]
GTX105265
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCTPS1
Overview
- SupplierGeneTex
- Product NameCTP synthase antibody [N1C1]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1503
- Target nameCTPS1
- Target descriptionCTP synthase 1
- Target synonymsCTPS, GATD5, GATD5A, IMD24, CTP synthase 1, CTP synthetase 1, UTP--ammonia ligase 1, cytidine 5'-triphosphate synthetase, cytidine 5-prime triphosphate synthetase
- HostRabbit
- IsotypeIgG
- Protein IDP17812
- Protein NameCTP synthase 1
- Scientific DescriptionThe catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chang CC, Jeng YM, Peng M, et al. CTP synthase forms the cytoophidium in human hepatocellular carcinoma. Exp Cell Res. 2017,361(2):292-299. doi: 10.1016/j.yexcr.2017.10.030Read this paper
- Calise SJ, Purich DL, Nguyen T, et al. 'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway. J Cell Sci. 2016,129(15):3042-52. doi: 10.1242/jcs.183400Read this paper
- Chang CC, Lin WC, Pai LM, et al. Cytoophidium assembly reflects upregulation of IMPDH activity. J Cell Sci. 2015,128(19):3550-5. doi: 10.1242/jcs.175265Read this paper
- Aughey GN, Grice SJ, Shen QJ, et al. Nucleotide synthesis is regulated by cytoophidium formation during neurodevelopment and adaptive metabolism. Biol Open. 2014,3(11):1045-56. doi: 10.1242/bio.201410165Read this paper
Datasheet
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