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CTP synthase antibody [N1C1]

Research Use Only
GTX105265
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCTPS1
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    CTP synthase antibody [N1C1]
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1503
  • Target name
    CTPS1
  • Target description
    CTP synthase 1
  • Target synonyms
    CTP synthase 1; CTP synthetase 1; CTPS; cytidine 5-prime triphosphate synthetase; cytidine 5'-triphosphate synthetase; GATD5; GATD5A; IMD24; UTP--ammonia ligase 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • CTP synthase forms the cytoophidium in human hepatocellular carcinoma. Chang CC et al., 2017 Dec 15, Exp Cell Res
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  • Rod and ring formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway. Calise SJ et al., 2016 Aug 1, J Cell Sci
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  • Cytoophidium assembly reflects upregulation of IMPDH activity. Chang CC et al., 2015 Oct 1, J Cell Sci
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  • Nucleotide synthesis is regulated by cytoophidium formation during neurodevelopment and adaptive metabolism. Aughey GN et al., 2014 Oct 17, Biol Open
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