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CU-CPT9b [2162962-69-6]

CU-CPT9b [2162962-69-6]

T7302
TargetMol Chemicals
CAS Number2162962-69-6
DownloadMSDS
Product group Chemicals
Molecular Weight251.28
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CU-CPT9b [2162962-69-6]
  • Delivery Days Customer
    9
  • CAS Number
    2162962-69-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    CU-CPT9b
  • Molecular Formula
    C16H13NO2
  • Molecular Weight
    251.28
  • Scientific Description
    CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1cc(ccc1O)-c1ccnc2cc(O)ccc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Small-molecule inhibition of TLR8 through stabilization of its resting state. Zhang S et al., 2018 Jan, Nat Chem Biol
    Read more