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CU-T12-9 [1821387-73-8]

CU-T12-9 [1821387-73-8]

T15017
TargetMol Chemicals
CAS Number1821387-73-8
Product group Chemicals
Estimated Purity99.93%
Molecular Weight362.31
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CU-T12-9 [1821387-73-8]
  • Delivery Days Customer
    4
  • CAS Number
    1821387-73-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    CU-T12-9
  • Estimated Purity
    99.93%
  • Molecular Formula
    C17H13F3N4O2
  • Molecular Weight
    362.31
  • Scientific Description
    CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-kappaB and invokes an elevation of the downstream effectors TNF-alpha, IL-10, and iNOS.
  • Shelf life instruction
    3 years
  • SMILES
    CNc1ccc(cc1-n1cnc(c1)-c1ccc(cc1)C(F)(F)F)[N+]([O-])=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200