![CU-T12-9 [1821387-73-8] CU-T12-9 [1821387-73-8]](https://www.targetmol.com/group3/M00/35/85/CgoaEWayIzeEJ0JDAAAAAE79T_4958.png)
CU-T12-9 [1821387-73-8]
T15017
CAS Number1821387-73-8
Product group Chemicals
Estimated Purity99.93%
Molecular Weight362.31
Overview
- SupplierTargetMol Chemicals
- Product NameCU-T12-9 [1821387-73-8]
- Delivery Days Customer4
- CAS Number1821387-73-8
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameCU-T12-9
- Estimated Purity99.93%
- Molecular FormulaC17H13F3N4O2
- Molecular Weight362.31
- Scientific DescriptionCU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-kappaB and invokes an elevation of the downstream effectors TNF-alpha, IL-10, and iNOS.
- Shelf life instruction3 years
- SMILESCNc1ccc(cc1-n1cnc(c1)-c1ccc(cc1)C(F)(F)F)[N+]([O-])=O
- Storage Instruction-20°C
- UNSPSC12352200