Cucurbitacin IIb [50298-90-3]

MedChem Express

Cucurbitacin IIb [50298-90-3]

10

50298-90-3

Research Use Only

99.0

C30H48O7

520.70

Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IkappaB and NF-kappaB (p65), blocks nuclear translocation of NF-kappaB (p65) and decreases mRNA levels of IkappaBalpha and TNF-alpha[1].

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2°C to 8°C

12352200