Cucurbitacin IIb [50298-90-3]

S0949
CAS Number50298-90-3
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameCucurbitacin IIb [50298-90-3]
- Delivery Days Customer9
- CAS Number50298-90-3
- CertificationResearch Use Only
- Scientific DescriptionCucurbitacin IIb (CuIIb, Dihydrocucurbitacin F, 25-deacetyl hemslecin A) inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IkappaB and NF-kappaB, blocks nuclear translocation of NF-kappaB and decreases mRNA levels of IkappaBalfa and TNF-alfa. Cucurbitacin IIb exhibits anti-inflammatory activity and induces apoptosis. Cucurbitacin IIb is isolated from Hemsleya amabilis.
- UNSPSC12352200