Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA835890ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA835890ESR1HU at dilution of 1:100
CUL5 Antibody
CSB-PA835890ESR1HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCUL5
Overview
- SupplierCusabio
- Product NameCUL5 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8065
- Target nameCUL5
- Target descriptioncullin 5
- Target synonymsCUL-5; cullin-5; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1); VACM1; VACM-1; vasopressin-activated calcium-mobilizing receptor 1; Vasopressin-activated calcium-mobilizing receptor-1
- HostRabbit
- IsotypeIgG
- Protein IDQ93034
- Protein NameCullin-5
- Scientific DescriptionCore component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203