Cuprizone

MedChem Express

Cuprizone [370-81-0]

10

370-81-0

Research Use Only

99.0

C14H22N4O2

278.356

Cuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes, including SOD1, cytochrome oxidase, and DbetaH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC)[1].

O=C(C(N/N=C1CCCCC\1)=O)N/N=C2CCCCC/2

-20°C,2°C to 8°C

12352200