![ICC/IF analysis of methanol-fixed HeLa cells using GTX50224 AMPK alpha 1 (phospho Ser496) antibody. ICC/IF analysis of methanol-fixed HeLa cells using GTX50224 AMPK alpha 1 (phospho Ser496) antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX50224/GTX50224_20190308_ICCIF_w_23060823_643.webp)
ICC/IF analysis of methanol-fixed HeLa cells using GTX50224 AMPK alpha 1 (phospho Ser496) antibody.
AMPK alpha 1 (phospho Ser487) antibody - Orthogonal Validated
![Research Use Only](static/images/certificates/ruo.jpg)
GTX50224
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetPRKAA1
Overview
- SupplierGeneTex
- Product NameAMPK alpha 1 (phospho Ser487) antibody - Orthogonal Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5562
- Target namePRKAA1
- Target descriptionprotein kinase AMP-activated catalytic subunit alpha 1
- Target synonyms5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; ACACA kinase; acetyl-CoA carboxylase kinase; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK alpha 1; AMPK subunit alpha-1; AMPK, alpha, 1; AMPKa1; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionThe protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203