anti-CDC45 antibody
ARG57313
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCDC45
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CDC45 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8318
- Target nameCDC45
- Target descriptioncell division cycle 45
- Target synonymsCDC45 cell division cycle 45 homolog; CDC45 cell division cycle 45-like; CDC45L; CDC45L2; CDC45-related protein; cell division control protein 45 homolog; cell division cycle 45 homolog; cell division cycle 45-like 2; human CDC45; MGORS7; PORC-PI-1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203