anti-TTF1 antibody
![Research Use Only](static/images/certificates/ruo.jpg)
ARG40777
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetNKX2-1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-TTF1 antibody
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7080
- Target nameNKX2-1
- Target descriptionNK2 homeobox 1
- Target synonymsBCH; BHC; homeobox protein NK-2 homolog A; homeobox protein Nkx-2.1; NK-2; NK-2 homolog A; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; thyroid nuclear factor 1; thyroid transcription factor 1; thyroid-specific enhancer-binding protein; TITF1; TTF1; TTF-1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias TTF1 with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203