BMS 777607 [1025720-94-8]
HY-12076
CAS Number1025720-94-8
Product group Chemicals
Estimated Purity98.49%
Molecular Weight512.89
Overview
- SupplierMedChem Express
- Product NameBMS 777607 [1025720-94-8]
- Delivery Days Customer10
- CAS Number1025720-94-8
- CertificationResearch Use Only
- Estimated Purity98.49%
- Molecular FormulaC25H19ClF2N4O4
- Molecular Weight512.89
- Scientific DescriptionBMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.
- SMILESO=C(NC1=CC=C(C(F)=C1)OC2=C(C(N)=NC=C2)Cl)C3=C(C=CN(C3=O)C4=CC=C(C=C4)F)OCC
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200