![GTX80204 IHC-P Image GTX80204 IHC-P Image](https://www.genetex.com/upload/website/prouct_img/normal/GTX80204/C-peptide-of-Proinsulin-antibody-C-PEP-01-Biotin-GTX80204-IHC-1_18121409_502.jpg)
GTX80204 IHC-P Image
C-Peptide antibody [C-PEP-01] (Biotin)
![Research Use Only](static/images/certificates/ruo.jpg)
GTX80204
ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, RadioImmunoAssay
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameC-Peptide antibody [C-PEP-01] (Biotin)
- Delivery Days Customer10
- ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, RadioImmunoAssay
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDc-pep-01
- Concentration1 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Production of pancreatic progenitor cells from human induced pluripotent stem cells using a three-dimensional suspension bioreactor system. Mihara Y et al., 2017 Nov, J Tissue Eng Regen MedRead more