GTX128428 IHC-P Image
Carbonic Anhydrase IX antibody
GTX128428
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameCarbonic Anhydrase IX antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.47 mg/ml
- IsotypeIgG
- Scientific DescriptionCarbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 3UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma. Hua KT et al., 2017 Jun 30, Sci RepRead more
- 5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells. Guo X et al., 2017 Jul 7, Sci RepRead more
- Comparison of 18F-fluoroazomycin-arabinofuranoside and 64Cu-diacetyl-bis(N4-methylthiosemicarbazone) in preclinical models of cancer. Valtorta S et al., 2013 Jul, J Nucl MedRead more
- Hypoxia-targeting dendritic MRI contrast agent based on internally hydroxy dendrimer for tumor imaging. Han Y et al., 2019 Aug, BiomaterialsRead more
- Intermittent hypoxia exacerbates tumor progression in a mouse model of lung cancer. Kang HS et al., 2020 Feb 5, Sci RepRead more
- Rhapontigenin inhibits TGF-beta-mediated epithelial-mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1alpha degradation. Yeh YH et al., 2016 May, Oncol RepRead more