CD44v3 Antibody
ORB534068
Overview
- SupplierBiorbyt
- Product NameCD44v3 Antibody
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierImmunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT IHC-P
- CertificationResearch Use Only
- Clone IDCDLA44v3-1
- IsotypeIgG
- Scientific DescriptionThis antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. It is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
- UNSPSC12352203