Clatherin Light Chain Antibody (LCA/LCB)
ORB386040
Overview
- SupplierBiorbyt
- Product NameClatherin Light Chain Antibody (LCA/LCB)
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierImmunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT IHC-P
- CertificationResearch Use Only
- Clone IDCLC/1421
- IsotypeIgG
- Scientific DescriptionRecognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
- UNSPSC12352203