CUL4A antibody, PAb
ORB66954
Overview
- SupplierBiorbyt
- Product NameCUL4A antibody, PAb
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWB:1:1000-1:5000 WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRabbit polyclonal to CUL4A.CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNAdamage-response proteins. CUL4A is a core component of multiple cullin-RING-based E3 ubiquitinproteinligase complexes which mediate the ubiquitination and subsequent proteasomal degradationof target proteins. As a scaffold protein, CUL4A may contribute to catalysis through positioning of thesubstrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complexis dependent on the neddylation of the cullin subunit. CUL4A may be involved in ubiquitination of JUN,P53, CDKN1B and HOXA9.
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203